Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection

The main function of regulatory T lymphocytes is to keep autoimmune responses at bay. Accordingly, it has been firmly established that the repertoire of CD4(+)CD25(+)Foxp3(+) regulatory T cells is enriched in autospecific cells. Differences in thymic positive and/or negative selection may account fo...

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Bibliografiska uppgifter
Huvudupphovsmän: Ribot, Julie, Enault, Geneviève, Pilipenko, Sylvie, Huchenq, Anne, Calise, Maryline, Hudrisier, Denis, Romagnoli, Paola, van Meerwijk, Joost PM
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Association of Immunologists 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577800/
https://ncbi.nlm.nih.gov/pubmed/17982064
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