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Genetic Variation in OAS1 Is a Risk Factor for Initial Infection with West Nile Virus in Man
West Nile virus (WNV) is a re-emerging pathogen that can cause fatal encephalitis. In mice, susceptibility to WNV has been reported to result from a single point mutation in oas1b, which encodes 2′–5′ oligoadenylate synthetase 1b, a member of the type I interferon-regulated OAS gene family involved...
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| Main Authors: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2642680/ https://ncbi.nlm.nih.gov/pubmed/19247438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000321 |
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