Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-κB

BACKGROUND & AIMS: Raf-1 kinase is a key regulator of a number of cellular processes, which promote the maintenance of a healthy colon epithelium. This study addresses the role of Raf in epithelial cell survival in response to dextran sulfate sodium (DSS)-induced injury and inflammation. METHODS...

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Main Authors: Edelblum, Karen L., Washington, M. Kay, Koyama, Tatsuki, Robine, Sylvie, Baccarini, Manuela, Polk, D. Brent
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640938/
https://ncbi.nlm.nih.gov/pubmed/18598699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.04.025
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