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Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that has a potent stimulatory effect on insulin release under conditions of normal glucose tolerance. However, its insulinotropic effect is reduced or even absent entirely in type 2 diabetic patients. In this study, we...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640485/ https://ncbi.nlm.nih.gov/pubmed/17505054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00070.2007 |
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