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T-cell Activation by Antigen-loaded pH-sensitive Hydrogel Particles In Vivo: The Effect of Particle Size

Polymeric carriers of protein antigens have great potential for improving the efficacy of vaccines and immunotherapeutics for diseases such as cancer. We recently developed a carrier system based on polyacrylamide hydrogel microparticles crosslinked with acid-labile moieties. After being phagocytose...

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Detalles Bibliográficos
Autores principales: Cohen, Joel A., Beaudette, Tristan T., Tseng, William W., Bachelder, Eric M., Mende, Ines, Engleman, Edgar G., Fréchet, Jean M. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640420/
https://ncbi.nlm.nih.gov/pubmed/19102625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc800338n
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