Antigen-loaded pH-sensitive hydrogel microparticles are taken up by dendritic cells with no requirement for targeting antibodies

Particle-based delivery of encapsulated antigen has great potential for improving vaccine constructs. In this study, we show that antigen-loaded, pH-sensitive hydrogel microparticles are taken up and presented by bone marrow-derived dendritic cells (BMDCs) in vitro and are taken up by dendritic cell...

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Bibliographic Details
Main Authors: Ruff, Laura E., Mahmoud, Enas A., Sankaranarayanan, Jagadis, Morachis, José M., Katayama, Carol D., Corr, Maripat, Hedrick, Stephen M., Almutairi, Adah
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3535018/
https://ncbi.nlm.nih.gov/pubmed/23060228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2ib20109g
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