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Microarray-based estimation of SNP allele-frequency in pooled DNA using the Langmuir kinetic model

BACKGROUND: High throughput genotyping of single nucleotide polymorphisms (SNPs) for genome-wide association requires technologies for generating millions of genotypes with relative ease but also at a reasonable cost and with high accuracy. In this work, we have developed a theoretical approach to e...

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Main Authors: Yin, Bin-Cheng, Li, Honghua, Ye, Bang-Ce
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640397/
https://ncbi.nlm.nih.gov/pubmed/19087310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-605
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