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Microarray-based estimation of SNP allele-frequency in pooled DNA using the Langmuir kinetic model
BACKGROUND: High throughput genotyping of single nucleotide polymorphisms (SNPs) for genome-wide association requires technologies for generating millions of genotypes with relative ease but also at a reasonable cost and with high accuracy. In this work, we have developed a theoretical approach to e...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640397/ https://ncbi.nlm.nih.gov/pubmed/19087310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-9-605 |
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