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PPC: an algorithm for accurate estimation of SNP allele frequencies in small equimolar pools of DNA using data from high density microarrays

Robust estimation of allele frequencies in pools of DNA has the potential to reduce genotyping costs and/or increase the number of individuals contributing to a study where hundreds of thousands of genetic markers need to be genotyped in very large populations sample sets, such as genome wide associ...

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Détails bibliographiques
Auteurs principaux: Brohede, Jesper, Dunne, Rob, McKay, James D., Hannan, Garry N.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1240117/
https://ncbi.nlm.nih.gov/pubmed/16199750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni142
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