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Mouse ES-cell-based functional assay to evaluate mutations in BRCA2
Individuals with mutations in breast cancer susceptibility genes, BRCA1 and BRCA2 have up to 80% risk of developing breast cancer by the age of 70. Sequencing based genetic tests are now available to identify mutation carriers in effort to reduce mortality through prevention and early diagnosis. How...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2640324/ https://ncbi.nlm.nih.gov/pubmed/18607349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1719 |
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