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Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

Failure of oligodendrocyte precursor cell (OPC) differentiation contributes significantly to failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases. Although the reasons for this failure are not completely understood, several lines of evidence point to factors present fo...

詳細記述

保存先:
書誌詳細
主要な著者: Baer, Alexandra S., Syed, Yasir A., Kang, Sung Ung, Mitteregger, Dieter, Vig, Raluca, ffrench-Constant, Charles, Franklin, Robin J. M., Altmann, Friedrich, Lubec, Gert, Kotter, Mark R.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640211/
https://ncbi.nlm.nih.gov/pubmed/19208690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn334
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