Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

Failure of oligodendrocyte precursor cell (OPC) differentiation contributes significantly to failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases. Although the reasons for this failure are not completely understood, several lines of evidence point to factors present fo...

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Bibliografiske detaljer
Main Authors: Baer, Alexandra S., Syed, Yasir A., Kang, Sung Ung, Mitteregger, Dieter, Vig, Raluca, ffrench-Constant, Charles, Franklin, Robin J. M., Altmann, Friedrich, Lubec, Gert, Kotter, Mark R.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640211/
https://ncbi.nlm.nih.gov/pubmed/19208690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn334
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