Myelin-mediated inhibition of oligodendrocyte precursor differentiation can be overcome by pharmacological modulation of Fyn-RhoA and protein kinase C signalling

Failure of oligodendrocyte precursor cell (OPC) differentiation contributes significantly to failed myelin sheath regeneration (remyelination) in chronic demyelinating diseases. Although the reasons for this failure are not completely understood, several lines of evidence point to factors present fo...

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Главные авторы: Baer, Alexandra S., Syed, Yasir A., Kang, Sung Ung, Mitteregger, Dieter, Vig, Raluca, ffrench-Constant, Charles, Franklin, Robin J. M., Altmann, Friedrich, Lubec, Gert, Kotter, Mark R.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2009
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2640211/
https://ncbi.nlm.nih.gov/pubmed/19208690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awn334
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