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Characterization of the nucleation barriers for protein aggregation and amyloid formation

Despite the complexity and the specificity of the amino acid code, a variety of peptides and proteins unrelated in sequence and function exhibit a common behavior and assemble into highly organized amyloid fibrils. The formation of such aggregates is often described by a nucleation and growth mechan...

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Détails bibliographiques
Auteurs principaux: Auer, Stefan, Dobson, Christopher M., Vendruscolo, Michele
Format: Artigo
Langue:Inglês
Publié: HFSP Publishing 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2639838/
https://ncbi.nlm.nih.gov/pubmed/19404419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2976/1.2760023
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