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Pathology is alleviated by doxycycline in a laminin-α2-null model of congenital muscular dystrophy
OBJECTIVE: Congenital muscular dystrophy type 1A (MDC1A) is an autosomal recessive disease that is caused by loss-of-function mutations in the laminin-α2 gene and results in motor nerve and skeletal muscle dysfunction. In a previous study, we used genetic modifications to show that inappropriate ind...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2639627/ https://ncbi.nlm.nih.gov/pubmed/19086074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21523 |
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