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Charge Carrier Field Emission Determines the Number of Charges on Native State Proteins in Electrospray Ionization
Although multiple charging in electrospray ionization (ESI) is essential to protein mass spectrometry, the underlying mechanism of multiple charging has not been explicated. Here, we present a new theory to describe ESI of native-state proteins and predict the number of excess charges on proteins in...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638767/ https://ncbi.nlm.nih.gov/pubmed/18461930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja801280c |
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