Methotrexate for the treatment of juvenile idiopathic arthritis: process to approval for JIA indication in Japan

Methotrexate (MTX), the primary treatment for the articular-type juvenile idiopathic arthritis (JIA), is effective and brings about radiological improvement. Patient compliance is good, and it is recognized that its known side effects, namely, disruption of liver function and induction of pulmonary...

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Main Authors: Mori, Masaaki, Naruto, Takuya, Imagawa, Tomoyuki, Murata, Takuji, Takei, Syuji, Tomiita, Minako, Itoh, Yasuhiko, Fujikawa, Satoshi, Yokota, Shumpei
Formato: Artigo
Idioma:Inglês
Publicado: Springer Japan 2008
Assuntos:
Review Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638602/
https://ncbi.nlm.nih.gov/pubmed/18815725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10165-008-0123-3
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