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Crystal Structures of Monomeric Actin Bound to Cytochalasin D

The fungal toxin cytochalasin D (CD) interferes with the normal dynamics of the actin cytoskeleton by binding to the barbed end of actin filaments. Despite its widespread use as a tool for studying actin-mediated processes, the exact location and nature of its binding to actin has not been previousl...

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Detalhes bibliográficos
Main Authors: Nair, Usha B., Joel, Peteranne B., Wan, Qun, Lowey, Susan, Rould, Mark A., Trybus, Kathleen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638586/
https://ncbi.nlm.nih.gov/pubmed/18938176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.09.082
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