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Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
BACKGROUND: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segments in the germline. Partitioning the functional antibody sequences to their sourcing germline gene segments is vital not o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2638160/ https://ncbi.nlm.nih.gov/pubmed/19091020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S12-S20 |
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