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Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies

BACKGROUND: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segments in the germline. Partitioning the functional antibody sequences to their sourcing germline gene segments is vital not o...

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Hlavní autoři: Wang, Xiaojing, Wu, Di, Zheng, Siyuan, Sun, Jing, Tao, Lin, Li, Yixue, Cao, Zhiwei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2638160/
https://ncbi.nlm.nih.gov/pubmed/19091020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-S12-S20
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