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The antioxidant function of the p53 tumor suppressor

It is widely accepted that the p53 tumor suppressor restricts abnormal cells by induction of growth arrest, or by triggering apoptosis. Here we show that in addition p53 protects the genome from oxidation by reactive oxygen species (ROS), a major cause for DNA damage and genetic instability. In the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sablina, Anna A., Budanov, Andrei V., Ilyinskaya, Galina V., Agapova, Larissa S., Kravchenko, Julia E., Chumakov, Peter M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637821/
https://ncbi.nlm.nih.gov/pubmed/16286925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1320
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