The Macrophage Proinflammatory Response to Francisella tularensis LVS Requires Coordination of Multiple Signaling Pathways

The macrophage proinflammatory response to Francisella tularensis (Ft) LVS was shown previously to be TLR2-dependent. The observation that intracellular Ft LVS co-localizes with TLR2 and MyD88 inside macrophages suggested that Ft LVS might signal from within the phagosome. Macrophages infected with...

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Huvudupphovsmän: Cole, Leah E., Santiago, Araceli, Barry, Eileen, Kang, Tae Jin, Shirey, Kari Ann, Roberts, Zachary J., Elkins, Karen L., Cross, Alan S., Vogel, Stefanie N.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637793/
https://ncbi.nlm.nih.gov/pubmed/18453609
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