Toll-Like Receptor 2-Mediated Signaling Requirements for Francisella tularensis Live Vaccine Strain Infection of Murine Macrophages

Francisella tularensis, an aerobic, non-spore-forming, gram-negative coccobacillus, is the causative agent of tularemia. We reported previously that F. tularensis live vaccine strain (LVS) elicited strong, dose-dependent NF-κB reporter activity in Toll-like receptor 2 (TLR2)-expressing HEK293T cells...

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Autori principali: Cole, Leah E., Shirey, Kari Ann, Barry, Eileen, Santiago, Araceli, Rallabhandi, Prasad, Elkins, Karen L., Puche, Adam C., Michalek, Suzanne M., Vogel, Stefanie N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2007
Soggetti:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951974/
https://ncbi.nlm.nih.gov/pubmed/17517865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01868-06
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