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Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic–nuclear transport

The product of the c-abl protooncogene is a nonreceptor tyrosine kinase found in both the cytoplasm and the nucleus. We report herein that cell adhesion regulates the kinase activity and subcellular localization of c-Abl. When fibroblastic cells are detached from the extracellular matrix, kinase act...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lewis, Jean M., Baskaran, Rajasekaran, Taagepera, Salme, Schwartz, Martin A., Wang, Jean Y. J.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26376/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15174
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