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Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic–nuclear transport

The product of the c-abl protooncogene is a nonreceptor tyrosine kinase found in both the cytoplasm and the nucleus. We report herein that cell adhesion regulates the kinase activity and subcellular localization of c-Abl. When fibroblastic cells are detached from the extracellular matrix, kinase act...

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Bibliografische gegevens
Hoofdauteurs: Lewis, Jean M., Baskaran, Rajasekaran, Taagepera, Salme, Schwartz, Martin A., Wang, Jean Y. J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC26376/
https://ncbi.nlm.nih.gov/pubmed/8986783
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