Integrin regulation of c-Abl tyrosine kinase activity and cytoplasmic–nuclear transport

The product of the c-abl protooncogene is a nonreceptor tyrosine kinase found in both the cytoplasm and the nucleus. We report herein that cell adhesion regulates the kinase activity and subcellular localization of c-Abl. When fibroblastic cells are detached from the extracellular matrix, kinase act...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lewis, Jean M., Baskaran, Rajasekaran, Taagepera, Salme, Schwartz, Martin A., Wang, Jean Y. J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26376/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15174
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