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Complement component C5a mediates hemorrhage-induced intestinal damage

BACKGROUND: Complement has been implicated in the pathogenesis of intestinal damage and inflammation in multiple animal models. Although the exact mechanism is unknown, inhibition of complement prevents hemodynamic alterations in hemorrhage. MATERIALS/METHODS: C57Bl/6, complement 5 deficient (C5−/−)...

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Main Authors: Fleming, Sherry D., Phillips, Lauren M., Lambris, John D., Tsokos, George C.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637531/
https://ncbi.nlm.nih.gov/pubmed/18639891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.02.010
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