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Complement component C5a mediates hemorrhage-induced intestinal damage

BACKGROUND: Complement has been implicated in the pathogenesis of intestinal damage and inflammation in multiple animal models. Although the exact mechanism is unknown, inhibition of complement prevents hemodynamic alterations in hemorrhage. MATERIALS/METHODS: C57Bl/6, complement 5 deficient (C5−/−)...

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Détails bibliographiques
Auteurs principaux: Fleming, Sherry D., Phillips, Lauren M., Lambris, John D., Tsokos, George C.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637531/
https://ncbi.nlm.nih.gov/pubmed/18639891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.02.010
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