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Complement component C5a mediates hemorrhage-induced intestinal damage
BACKGROUND: Complement has been implicated in the pathogenesis of intestinal damage and inflammation in multiple animal models. Although the exact mechanism is unknown, inhibition of complement prevents hemodynamic alterations in hemorrhage. MATERIALS/METHODS: C57Bl/6, complement 5 deficient (C5−/−)...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637531/ https://ncbi.nlm.nih.gov/pubmed/18639891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2008.02.010 |
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