Lataa...
Prion Protein Modulates Cellular Iron Uptake: A Novel Function with Implications for Prion Disease Pathogenesis
Converging evidence leaves little doubt that a change in the conformation of prion protein (PrP(C)) from a mainly α-helical to a β-sheet rich PrP-scrapie (PrP(Sc)) form is the main event responsible for prion disease associated neurotoxicity. However, neither the mechanism of toxicity by PrP(Sc), no...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2009
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637434/ https://ncbi.nlm.nih.gov/pubmed/19212444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004468 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|