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Soluble Epoxide Hydrolase Inhibitors Reduce the Development of Atherosclerosis in Apolipoprotein E-Knockout Mouse Model
In order to determine whether sEH inhibitors influence atherosclerotic lesion formation, we utilized an established murine model of accelerated atherogenesis, ApoE knockout (−/−) mice. The sEH inhibitor, 1-adamantan-3-(5-(2-(2-ethylethoxy)ethoxy)pentyl)urea (AEPU) was delivered in drinking water. Al...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2637359/ https://ncbi.nlm.nih.gov/pubmed/18791465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0b013e318185fa3c |
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