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The Effect of Local Simvastatin Delivery Strategies on Mandibular Bone Formation In Vivo

Systemic simvastatin is known to reduce cholesterol and stimulate modest bone formation, but local surgical placement in polylactic acid domes causes robust bone formation and local swelling. A less invasive and more flexible injection protocol was studied to evaluate the bone-inducing effects compa...

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Detalhes bibliográficos
Main Authors: Lee, Yeonju, Schmid, Marian J., Marx, David B., Beatty, Mark W., Cullen, Diane M., Collins, Melissa, Reinhardt, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637035/
https://ncbi.nlm.nih.gov/pubmed/18255137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2007.12.045
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