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Subunit-Specific Effects of Isoflurane on Neuronal I(h) in HCN1 Knockout Mice

The ionic mechanisms that contribute to general anesthetic actions have not been elucidated, although increasing evidence has pointed to roles for subthreshold ion channels, such as the HCN channels underlying the neuronal hyperpolarization-activated cationic current (I(h)). Here, we used convention...

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Detalles Bibliográficos
Main Authors: Chen, Xiangdong, Shu, Shaofang, Kennedy, Dylan P., Willcox, Sarah C., Bayliss, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2637007/
https://ncbi.nlm.nih.gov/pubmed/18971302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01352.2007
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