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Drosophila hnRNP A1 homologs Hrp36/Hrp38 enhance U2-type versus U12-type splicing to regulate alternative splicing of the prospero twintron

During Drosophila embryogenesis, the transcription factor Prospero is critical for neuronal differentiation and axonal outgrowth. The prospero pre-mRNA undergoes alternative splicing, but is unique in that it harbors a rare twintron whereby one intron lies embedded within another. The innermost intr...

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Bibliographic Details
Main Authors: Borah, Sumit, Wong, Anthony C., Steitz, Joan A.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636732/
https://ncbi.nlm.nih.gov/pubmed/19196985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812826106
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