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Inhibition of β-catenin signaling causes defects in postnatal cartilage development

The Wnt/β-catenin signaling pathway is essential for normal skeletal development because conditional gain or loss of function of β-catenin in cartilage results in embryonic or early postnatal death. To address the role of β-catenin in postnatal skeletal growth and development, Col2a1-ICAT transgenic...

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Detalhes bibliográficos
Main Authors: Chen, Mo, Zhu, Mei, Awad, Hani, Li, Tian-Fang, Sheu, Tzong-Jen, Boyce, Brendan F., Chen, Di, O'Keefe, Regis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636704/
https://ncbi.nlm.nih.gov/pubmed/18397998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.020362
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