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Effect of double bond geometry in sphingosine base on the antioxidant function of sphingomyelin

We previously showed that sphingomyelin (SM) inhibits peroxidation of phosphatidylcholine (PC) and cholesterol. Since SM uniquely has a trans unsaturation in its sphingosine base, we investigated whether this feature is important for its antioxidant function. Substitution of the natural trans Δ(4)-d...

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Detalhes bibliográficos
Main Authors: Subbaiah, Papasani V., Sircar, Debajit, Lankalapalli, Ravi S., Bittman, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636625/
https://ncbi.nlm.nih.gov/pubmed/18952047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.10.005
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