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Effect of double bond geometry in sphingosine base on the antioxidant function of sphingomyelin

We previously showed that sphingomyelin (SM) inhibits peroxidation of phosphatidylcholine (PC) and cholesterol. Since SM uniquely has a trans unsaturation in its sphingosine base, we investigated whether this feature is important for its antioxidant function. Substitution of the natural trans Δ(4)-d...

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Autori principali: Subbaiah, Papasani V., Sircar, Debajit, Lankalapalli, Ravi S., Bittman, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636625/
https://ncbi.nlm.nih.gov/pubmed/18952047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.10.005
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