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Tumor-induced impairment of TCR signaling results in compromised functionality of tumor-infiltrating regulatory T cells

This study demonstrates, for the first time, that murine regulatory T (Treg) cells in the tumor microenvironment display both enhanced proliferation and reduced functionality. This enhanced proliferation, combined with decreased apoptosis, leads to an intratumoral accumulation of Treg cells with a u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lutsiak, M.E. Christine, Tagaya, Yutaka, Adams, Anthony J., Schlom, Jeffrey, Sabzevari, Helen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2636572/
https://ncbi.nlm.nih.gov/pubmed/18424706
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!