Loss of yata, a Novel Gene Regulating the Subcellular Localization of APPL, Induces Deterioration of Neural Tissues and Lifespan Shortening

BACKGROUND: The subcellular localization of membrane and secreted proteins is finely and dynamically regulated through intracellular vesicular trafficking for permitting various biological processes. Drosophila Amyloid precursor protein like (APPL) and Hikaru genki (HIG) are examples of proteins tha...

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Detalhes bibliográficos
Main Authors: Sone, Masaki, Uchida, Atsuko, Komatsu, Ayumi, Suzuki, Emiko, Ibuki, Ikue, Asada, Megumi, Shiwaku, Hiroki, Tamura, Takuya, Hoshino, Mikio, Okazawa, Hitoshi, Nabeshima, Yo-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635962/
https://ncbi.nlm.nih.gov/pubmed/19209226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004466
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