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Reassessment of the microbicidal activity of reactive oxygen species and hypochlorous acid with reference to the phagocytic vacuole of the neutrophil granulocyte

During phagocytosis, neutrophils undergo a burst of respiration in which oxygen is reduced to superoxide ([Formula: see text]), which dismutates to form H(2)O(2). Myeloperoxidase (MPO) is discharged from the cytoplasmic granules into the phagosome following particle ingestion. It is thought to utili...

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Detalhes bibliográficos
Main Authors: Reeves, Emer P., Nagl, Markus, Godovac-Zimmermann, Jasminca, Segal, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635949/
https://ncbi.nlm.nih.gov/pubmed/12867557
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