The coactivator CRTC1 promotes cell proliferation and transformation via AP-1

Regulation of gene expression in response to mitogenic stimuli is a critical aspect underlying many forms of human cancers. The AP-1 complex mediates the transcriptional response to mitogens, and its deregulation causes developmental defects and tumors. We report that the coactivator CRTC1 cyclic AM...

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Detalhes bibliográficos
Main Authors: Canettieri, Gianluca, Coni, Sonia, Della Guardia, Michele, Nocerino, Valentina, Antonucci, Laura, Di Magno, Laura, Screaton, Robert, Screpanti, Isabella, Giannini, Giuseppe, Gulino, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635810/
https://ncbi.nlm.nih.gov/pubmed/19164581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808749106
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