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PD-1 Regulates Neural Damage in Oligodendroglia-Induced Inflammation

We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role of the co-inhibitory molecule PD-1, a CD28-re...

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Autors principals: Kroner, Antje, Schwab, Nicholas, Ip, Chi Wang, Leder, Christoph, Nave, Klaus-Armin, Mäurer, Mathias, Wiendl, Heinz, Martini, Rudolf
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2635015/
https://ncbi.nlm.nih.gov/pubmed/19197390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004405
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