Immune Cells Contribute to Myelin Degeneration and Axonopathic Changes in Mice Overexpressing Proteolipid Protein in Oligodendrocytes

Overexpression of the major myelin protein of the CNS, proteolipid protein (PLP), leads to late-onset degeneration of myelin and pathological changes in axons. Based on the observation that in white matter tracts of these mutants both CD8+ T-lymphocytes and CD11b+ macrophage-like cells are numerical...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Ip, Chi Wang, Kroner, Antje, Bendszus, Martin, Leder, Christoph, Kobsar, Igor, Fischer, Stefan, Wiendl, Heinz, Nave, Klaus-Armin, Martini, Rudolf
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2006
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673777/
https://ncbi.nlm.nih.gov/pubmed/16885234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1921-06.2006
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