Oncogenic kinase NPM/ALK induces through STAT3 expression of immunosuppressive protein CD274 (PD-L1, B7-H1)

The mechanisms of malignant cell transformation caused by the oncogenic, chimeric nucleophosmin (NPM)/anaplastic lymphoma kinase (ALK) remain only partially understood, with most of the previous studies focusing mainly on the impact of NPM/ALK on cell survival and proliferation. Here we report that...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Marzec, Michal, Zhang, Qian, Goradia, Ami, Raghunath, Puthiyaveettil N., Liu, Xiaobin, Paessler, Michele, Wang, Hong Yi, Wysocka, Maria, Cheng, Mangeng, Ruggeri, Bruce A., Wasik, Mariusz A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634900/
https://ncbi.nlm.nih.gov/pubmed/19088198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810958105
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados