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Adaptive protein evolution grants organismal fitness by improving catalysis and flexibility

Protein evolution is crucial for organismal adaptation and fitness. This process takes place by shaping a given 3-dimensional fold for its particular biochemical function within the metabolic requirements and constraints of the environment. The complex interplay between sequence, structure, function...

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Detalhes bibliográficos
Main Authors: Tomatis, Pablo E., Fabiane, Stella M., Simona, Fabio, Carloni, Paolo, Sutton, Brian J., Vila, Alejandro J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634896/
https://ncbi.nlm.nih.gov/pubmed/19098096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807989106
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