Tissue-specific PKA inhibition using a chemical genetic approach and its application to studies on sperm capacitation

Studies on cAMP signaling and protein kinase A (PKA) function in vivo are limited by the lack of highly specific inhibitors that can be used in primary cell culture and whole animals. Previously we reported that a mutation in the ATP binding pocket of a catalytic subunit (Cα) of PKA confers sensitiv...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Morgan, Daniel J., Weisenhaus, Michael, Shum, Sara, Su, Thomas, Zheng, Ruimao, Zhang, Chao, Shokat, Kevan M., Hille, Bertil, Babcock, Donner F., McKnight, G. Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634883/
https://ncbi.nlm.nih.gov/pubmed/19074277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810971105
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados