Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7

Activation of Toll-like receptors (TLR) contributes to the initiation and maintenance of chronic inflammation in autoimmune diseases, yet repeated exposure to a TLR agonist can induce hyporesponsiveness to subsequent TLR stimulation. Here, we used a synthetic TLR7 agonist, 9-benzyl-8-hydroxy-2-(2-me...

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Hauptverfasser: Hayashi, Tomoko, Gray, Christine S., Chan, Michael, Tawatao, Rommel I., Ronacher, Lisa, McGargill, Maureen A., Datta, Sandip K., Carson, Dennis A., Corr, Maripat
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634806/
https://ncbi.nlm.nih.gov/pubmed/19188597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813037106
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