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TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch
During the course of breast cancer progression, normally dormant tumour-promoting effects of transforming growth factor β (TGFβ), including migration, invasion, and metastasis are unmasked. In an effort to identify mechanisms that regulate the pro-migratory TGFβ ‘switch' in mammary epithelial c...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Nature Publishing Group
2009
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634733/ https://ncbi.nlm.nih.gov/pubmed/19096363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.266 |
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