TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch

During the course of breast cancer progression, normally dormant tumour-promoting effects of transforming growth factor β (TGFβ), including migration, invasion, and metastasis are unmasked. In an effort to identify mechanisms that regulate the pro-migratory TGFβ ‘switch' in mammary epithelial c...

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Main Authors: Liu, Irwin M, Schilling, Stephen H, Knouse, Kristin A, Choy, Lisa, Derynck, Rik, Wang, Xiao-Fan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634733/
https://ncbi.nlm.nih.gov/pubmed/19096363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.266
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