The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy

Basal-like tumours account for 15% of invasive breast carcinomas and are associated with a poorer prognosis and resistance to therapy. We hypothesised that this aggressive phenotype is because of an intrinsically elevated hypoxic response. Microarrayed tumours from 188 patients were stained for hypo...

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Detalhes bibliográficos
Main Authors: Tan, E Y, Yan, M, Campo, L, Han, C, Takano, E, Turley, H, Candiloro, I, Pezzella, F, Gatter, K C, Millar, E K A, O'Toole, S A, McNeil, C M, Crea, P, Segara, D, Sutherland, R L, Harris, A L, Fox, S B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634728/
https://ncbi.nlm.nih.gov/pubmed/19165203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604844
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